Dr. Carla Siegfried is the Jacquelyn E. and Allan E. Kolker, MD Distinguished Professor of Ophthalmology and serves as the Vice Chair for Strategic Initiatives at Washington University in St. Louis, Missouri. She completed her medical school training at the University of Missouri-Kansas City integrated undergraduate-graduate program. Following a residency in ophthalmology at the University of Illinois Eye and Ear Infirmary in Chicago, she completed a glaucoma fellowship at Northwestern University. Dr. Siegfried returned to her home of St. Louis and has served on faculty at Washington University since 1994. She has trained numerous fellows and residents, including service as Residency Program director and Glaucoma fellowship director.

Dr. Siegfried manages a busy clinical practice as well as her research endeavors in the clinic and the laboratory. As a glaucoma clinician managing complex tertiary consulations, she strongly believes in the importance of the physician-patient relationship and the impact of patient comprehension of disease and treatment options. Her National Eye Institute-supported research focuses on mitochondrial function and gene expression in the trabecular meshwork as it relates to racial disparities of glaucoma. She received the Shaffer prize in 2018 from the Glaucoma Research Foundation recognizing innovative glaucoma research and was inducted into the American Ophthalmological Society in 2019. She has also participated in several clinical studies including the Ocular Hypertension Treatment Study. She serves on the Editorial Board for Ophthalmology and Ophthalmology Glaucoma.

She has contributed to numerous committees of the American Academy of Ophthalmology and currently serves as Chairperson of the AAO Ethics Committee and Past President of the American Glaucoma Society. She has received the Secretariat and Senior Achievement Awards from the AAO for her dedicated efforts.